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The 28S ribosomal RNA (rRNA) is a major structural and functional component of the large subunit (60S) of eukaryotic cytoplasmic ribosomes. It is essential for the assembly, stability, and function of the ribosome during protein synthesis. While it serves a vital role in protein synthesis and can be indirectly impacted by drugs targeting translation, it is typically not considered a direct therapeutic target itself. Its sequence is used for phylogenetic studies.
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