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Eukaryotic translation elongation factor 1 alpha 1 pseudogene
- Molecular classification
- Other (Pseudogene)
01
Overview
The eukaryotic translation elongation factor 1 alpha 1 pseudogene (ENSG00000270413) is a processed pseudogene derived from the parental gene EEF1A1, which encodes a key component of the protein translation machinery in eukaryotes. Unlike its parent gene, the pseudogene does not code for a functional protein and generally has no direct biological activity. Pseudogenes, however, may play indirect regulatory roles in gene networks, particularly via non-coding RNAs, and their aberrant expression has been implicated in cancer and other diseases. The presence of pseudogenes can complicate genetic analysis and diagnostic workflows, but they are not considered therapeutic targets[2][5][7].
- Other names
- EEF1A1 pseudogeneEukaryotic translation elongation factor 1 alpha 1 pseudogene X (where X is the number, e.g., "pseudogene 13")EEF1A1P
02
Biological functions
Other (No known function; possibly regulatory via non-coding RNA mechanisms)May participate in gene regulation network or expression modulation of parent gene (EEF1A1) through non-coding RNA effects in certain contextsNo canonical role in translation or protein synthesis (the parent gene performs these functions, not the pseudogene)
03
Disease associations
Other (Not a direct disease gene; non-functional and not causal for disease itself)Possible involvement in gene regulation in cancer and other diseases through RNA effectsPseudogenes may confound diagnostic genetic testing or variant calling leading to delays or errors
04
Safety considerations
Possible diagnostic confusion: Classification errors or gene misannotation (e.g., miscalling a deletion) can affect genomic diagnosticsNo therapeutic safety concerns, as it is not a drug target
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