Target intelligence / Profile preview

Eukaryotic translation elongation factor 1 alpha 1 pseudogene 11 (EEF1A1P11)

Target
EEF1A1P11
Molecular classification
Other, Processed pseudogene
01

Overview

EEF1A1P11 is a processed pseudogene derived from the eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) gene. Pseudogenes like EEF1A1P11 are genomic DNA sequences similar to conventional genes but are typically non-functional due to mutations or lack of necessary regulatory elements. EEF1A1P11 is listed as located on chromosome 1p21.3 and has been noted in bioinformatic and cancer genomic studies, but there is no evidence that it encodes a protein or has a direct biological function[4][2]. While some EEF1A1 pseudogenes have been observed in the context of various cancers and metabolic diseases, these associations are largely correlative, and EEF1A1P11 itself is not a recognized biological or drug target[4][2]. EEF1A1P11 should not be confused with the functional protein eukaryotic translation elongation factor 1 alpha 1 (EEF1A1), which is vital for protein synthesis and has well-described enzymatic activity and biological roles[1][3][5].

Other names
EEF1A1 pseudogene 11EEF1A1P11Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) pseudogene 11
02

Mechanism of action

null (not a functional target)

03

Biological functions

Other (pseudogenes generally lack protein-coding and biological function, but can sometimes play regulatory roles)
04

Disease associations

Other (EEF1A1 pseudogenes, including EEF1A1P11, have been noted in association studies with several diseases, such as osteosarcoma, lung cancer, colon cancer, and type 2 diabetes mellitus, but direct functional evidence for EEF1A1P11 involvement is lacking)

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