Eukaryotic translation elongation factor 1 alpha 1 pseudogene 14 (EEF1A1P14)

EEF1A1P14 is a processed pseudogene derived from the EEF1A1 gene family, located at 1q31.3 in the human genome and spanning 1666 nucleotides[2]. It does not encode a functional protein but is one of more than 40 EEF1A1-related pseudogenes dispersed throughout the human genome[2]. While the parent gene EEF1A1 encodes a major translation elongation factor critical for protein biosynthesis, EEF1A1P14 itself has no established protein-coding function. Some EEF1A1 pseudogenes have been weakly associated with various cancers, usually by correlative genomic analyses, but there are no well-characterized functional or pathological roles for EEF1A1P14 specifically[2][3][4][5]. EEF1A1P14 and related pseudogenes are sometimes transcribed and may act as regulatory non-coding RNAs affecting the expression of the parental EEF1A1 gene or other genes; however, functional details for EEF1A1P14 are not available[2]. In summary, EEF1A1P14 is a non-coding processed pseudogene, generally not considered a therapeutic target, with no direct biological, mechanistic, or clinical roles described to date[2][4][5].

Other names

EEF1AL12Eukaryotic translation elongation factor 1 alpha-like 12 pseudogeneEukaryotic translation elongation factor 1 alpha 1 (EEF1A1) pseudogene

No established mechanism since there are no drugs targeting this pseudogene.