Eukaryotic translation elongation factor 1 alpha 1 pseudogene 3 (EEF1A1P3)

EEF1A1P3 is a transcribed unprocessed pseudogene located on chromosome 13 that produces a long non-coding RNA (lncRNA) of 575 nucleotides[2]. Unlike its functional parent gene EEF1A1, which encodes a crucial protein translation elongation factor, EEF1A1P3 does not code for a functional protein. The pseudogene contains four non-coding exons and is classified as a transcribed unprocessed pseudogene[2]. It is expressed in various tissues including the heart (particularly the left ventricle), trachea, liver, testis, kidney, bladder, and brain, with lower expression in the adrenal gland, colon, and pituitary gland[2]. As a lncRNA, EEF1A1P3 may function in gene regulation by modulating expression at both transcriptional and post-transcriptional levels, potentially acting as a microRNA decoy, though its exact biological role remains unclear[2]. Chromosome 13, where EEF1A1P3 is located, carries several cancer-related genes including BRCA2 and RB1, suggesting potential involvement in oncogenic processes[2].

Other names

EEF1A1 pseudogeneEEF1ALEEF1AL1EEF1DP3eukaryotic translation elongation factor 1 alpha 2 pseudogeneeukaryotic translation elongation factor 1 alpha-like 1 pseudogene