Eukaryotic translation elongation factor 1 alpha 1 pseudogene 35 (EEF1A1P35)

EEF1A1P35 is a processed pseudogene (retrocopy) of the Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) gene, located on chromosome 4:135045464-135046850 (according to EMBL-EBI, but some resources note other locations such as chromosome 13 based on different pseudogene annotations)[2][6]. Unlike its parental gene EEF1A1, which encodes a key GTPase involved in the ribosomal elongation phase of protein synthesis, EEF1A1P35 does not encode a functional protein. Processed pseudogenes such as EEF1A1P35 are created by retrotransposition events and typically lack regulatory elements or are not transcribed; even when transcribed, they generally produce non-coding RNAs with no established biological function[1][6]. While some EEF1A1 pseudogenes have been associated generally with genomic instability or altered expression in cancers, there is no evidence that EEF1A1P35 functions as a therapeutic target, nor is it known to have a direct role in disease, biomarker utility, or drug interaction[1][4][6]. Key additional points: - **Not a therapeutic target:** EEF1A1P35 is not a receptor, enzyme, transporter, or druggable entity[1][4][6]. - **No known protein product:** As a pseudogene, EEF1A1P35 does not produce an elongation factor protein, and there are no known phenotypic or disease associations specific to this pseudogene[1][6]. - **Aliases:** EEF1A1P35 is the primary alias in major genetic databases[4][6]. - **Genomic location:** Located on chromosome 4:135045464-135046850 in some sources (EMBL-EBI), but also referenced at chr13:10835978-10837581 in others, which reflects differences in pseudogene annotation conventions[2][6]. - **Family:** Belongs to the eukaryotic translation elongation factor 1 alpha pseudogene family, a group of numerous retrotransposed copies of EEF1A1 throughout the genome[1]. - **Not misspelled:** The query name is accurate and refers to a real genomic feature; it is not a protein-coding gene, drug target, nor directly disease-associated[1][4][6]. There is no evidence of EEF1A1P35 functioning as a receptor, enzyme, transporter, biomarker, or as a target for any known drugs[1][2][4][6].

Other names

EEF1A1P35