Target intelligence / Profile preview

Eukaryotic translation elongation factor 1 alpha 1 pseudogene 48 (EEF1A1P48)

Target
EEF1A1P48
Molecular classification
Other
01

Overview

Eukaryotic translation elongation factor 1 alpha 1 pseudogene 48 is one of at least 42 pseudogenes related to EEF1A1 in the human genome[2]. It is considered a retropseudogene, meaning it likely arose from the retrotransposition of the EEF1A1 mRNA but does not encode a functional protein[2]. Pseudogenes like EEF1A1P48 are non-coding segments of DNA that share sequence similarity with their parent gene but usually lack regulatory elements and/or contain disabling mutations[2][4]. EEF1A1P48 itself has no known protein product or direct biological role and is not considered a therapeutic or functional molecular target. The functional version of this gene (EEF1A1) is a GTPase involved in translational elongation during protein synthesis, but the pseudogene does not perform this function[1][2][4][6].\n\nKey point:\nEEF1A1P48 is not a functional gene, receptor, or therapeutic target. It is a noncoding pseudogene with no established biological function, disease relevance, or clinical utility. If seeking a drug target, the canonical protein is \"Eukaryotic translation elongation factor 1 alpha 1\" (eEF1A1), not EEF1A1P48.

Other names
EEF1A1P48eukaryotic translation elongation factor 1 alpha 1 pseudogene 48
02

Mechanism of action

None (not a druggable or functional target)

03

Biological functions

None (as a pseudogene, it does not encode a functional protein and has no known biological function)
04

Disease associations

None (no direct disease associations reported; certain EEF1A1 pseudogenes have been weakly linked to cancer and other diseases, but EEF1A1P48 specifically is not well characterized)
05

Safety considerations

None (not therapeutically targeted)
06

Interacting drugs

None (no drugs are known to target a pseudogene)
07

Biomarkers

None (not established as a biomarker)

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