Eukaryotic translation elongation factor 1 epsilon 1 pseudogene 1 (EEF1E1P1)

EEF1E1P1 (Eukaryotic translation elongation factor 1 epsilon 1 pseudogene 1) is classified as a **processed pseudogene** located on chromosome 2q13. It shows high sequence similarity (93.47%) to the EEF1E1 mRNA transcript variant 1 but does not correspond to transcript variant 2, suggesting its likely origin from a retrotransposition event involving variant 1 mRNA only[2]. EEF1E1P1 is not known to encode a functional protein, and no current research has elucidated any direct biological function, disease association, or therapeutic target potential for this pseudogene. While its parental gene, EEF1E1 (also known as AIMP3 or P18), participates as an auxiliary factor in the aminoacyl-tRNA synthetases complex and may act as a tumor suppressor, EEF1E1P1 itself is not known to participate in these processes or be expressed functionally[2][3][4]. The only mention in disease contexts is an incidental report in a coronary artery disease genetic study, but its direct significance remains unclear[2].