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Eukaryotic translation initiation factor 3 subunit E pseudogene 3 (EIF3EP3) is classified as a pseudogene in the human genome[4][1]. Pseudogenes are genomic DNA sequences similar to normal genes but are non-functional; they are typically unable to encode functional proteins due to mutations or lack of regulatory elements. EIF3EP3 shares sequence homology with the protein-coding gene EIF3E, which is a true subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. However, as a pseudogene, EIF3EP3 does not produce a functional protein and has no confirmed biological function, disease association, or drug interactions. It is not considered a therapeutic target[4][1]. Key points: - EIF3EP3 is not a receptor, enzyme, transporter, or recognized therapeutic target[4][1]. - No known associated biological functions, roles in disease, drug interactions, or use as a biomarker have been described for this pseudogene[4][1]. - The entry is likely included for genomic annotation purposes and should not be considered for drug development or therapeutic targeting. If a protein-coding gene is of interest, refer instead to Eukaryotic translation initiation factor 3 subunit E (EIF3E, also known as EIF3S6), which is functionally relevant in translation initiation[3][5].
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