Eukaryotic translation initiation factor 3 subunit F pseudogene 3 (EIF3FP3)

EIF3FP3 is a human pseudogene, named for its sequence similarity to "eukaryotic translation initiation factor 3 subunit F" (EIF3F)[2][3]. Pseudogenes such as EIF3FP3 do not code for functional proteins and are generally not considered therapeutic targets, biological markers, or contributors to disease pathogenesis. They may originate from gene duplication or retrotransposition events but typically lack the necessary elements for correct expression and protein production. There is no evidence indicating EIF3FP3 is expressed or functional; its primary significance is as a genomic sequence related to EIF3F, the true protein-coding gene that is a subunit of a critical translation initiation complex[3][1]. No drug interactions, biomarkers, disease associations, or safety concerns are documented for EIF3FP3, and it is not targeted in current therapeutic or diagnostic applications. There is something wrong with this target for most research and clinical uses: EIF3FP3 is not a functional protein, receptor, or enzyme—instead, it is a pseudogene. Any reference to using EIF3FP3 as a drug target, biomarker, or functional molecular entity is incorrect. If information regarding translation initiation, disease association, or drug interactions is needed, it should relate to the canonical functional gene EIF3F (eukaryotic translation initiation factor 3 subunit F), not the pseudogene variant.

Other names

hCG15200EIF3FP3