Eukaryotic translation initiation factor 3 subunit I pseudogene (EIF3IP1)

This target is a **pseudogene** associated with the eukaryotic translation initiation factor 3 (eIF3) complex, specifically a subunit I/alpha. The eIF3 complex is a large, multi-subunit factor essential for the initiation of translation in eukaryotes and is involved in recruiting the 40S ribosomal subunit, mRNA, and initiator tRNA for protein synthesis[3]. However, this entry corresponds to a pseudogene, meaning it does **not encode a functional protein** and does not have a canonical biological role. Pseudogenes can occasionally be transcribed or have regulatory functions, but there is **no evidence that this particular pseudogene serves as a therapeutic target, biomarker, or that it is implicated directly in disease or drug response**. The core eIF3 complex and its functional subunits (such as eIF3J, eIF3I, etc.) are crucial in translation and sometimes in cancer biology, but **pseudogenes are generally excluded from such roles**[1][3][7]. ### Additional interpretive notes: - The **Ensembl ID ENSG00000225122** designates this gene as a *pseudogene*, not a protein-coding gene. - It is not considered a canonical or therapeutic target in human disease or drug development. - If you intended to retrieve data on a functional protein (such as eIF3I or eIF3J), consider using the specific protein-coding gene, not the pseudogene. - There is **nothing erroneous in the name itself** if referring to the pseudogene, but if the intent was to identify a functional, druggable target, **this entry is not correct**.

Other names

eIF3i pseudogeneEIF3IP1eukaryotic translation initiation factor 3, subunit I, pseudogene 1