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ENSG00000270335 is a pseudogene related to the eukaryotic translation initiation factor 3, subunit J (EIF3J) gene. Pseudogenes are non-functional sequences of genomic DNA that are similar to normal genes but typically lack the ability to encode functional proteins[2][4]. They arise from gene duplication or retrotransposition events but often acquire disabling mutations or lack necessary regulatory elements, rendering them incapable of normal gene expression[2]. This pseudogene does not produce an active protein, is not considered a druggable therapeutic target, and should not be confused with the active EIF3J gene, which plays a role in translation initiation[1][3][5].
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