Eukaryotic translation initiation factor 3 subunit L pseudogene 2 (EIF3LP2)

Eukaryotic translation initiation factor 3 subunit L pseudogene 2 (EIF3LP2) is a human pseudogene, meaning it is a genomic DNA sequence related to the functional gene encoding the eukaryotic translation initiation factor 3 subunit L (EIF3L), but it does not produce a functional protein. Pseudogenes like EIF3LP2 generally arise via gene duplication or retrotransposition followed by accumulation of disabling mutations. EIF3LP2 is catalogued in gene databases such as NCBI Gene (ID: 143341) and Ensembl (ENSG00000233837). There is no evidence for EIF3LP2 involvement in disease, biological function, or as a drug target. EIF3LP2 is distinct from EIF3L (the protein-coding gene for a subunit of the eukaryotic translation initiation factor 3 complex that is involved in protein synthesis initiation). The pseudogene EIF3LP2 does not encode a protein and is not part of the active translation machinery in cells. No therapeutic, diagnostic, or biomarker roles have been described for EIF3LP2. This target is a validated pseudogene, not considered a druggable protein or a molecular therapeutic target.

Other names

EIF3EIPP2EIF3S6IPP2eukaryotic translation initiation factor 3, subunit 6 interacting protein pseudogene 2eukaryotic translation initiation factor 3, subunit 6 interacting protein, putative pseudogeneeukaryotic translation initiation factor 3, subunit E interacting protein pseudogene 2EIF3LP2