Eukaryotic translation initiation factor 3 subunit L pseudogene 3 (EIF3LP3)

EIF3LP3 is classified as a pseudogene, meaning it is a DNA sequence similar to the functional gene EIF3L but is generally considered nonfunctional at the protein-coding level[1][2][4]. Pseudogenes like EIF3LP3 are often derived from duplication or retrotransposition events and typically contain mutations such as insertions, deletions, or stop codons that prevent them from encoding a functional protein[3][5]. While EIF3LP3 is annotated in the human genome, there is no evidence for its direct involvement as a therapeutic or pharmacological target, nor as a biomarker or disease gene. More broadly, pseudogenes can sometimes exert regulatory roles in gene expression. This can include acting as decoys for microRNAs (miRNA), producing non-coding RNAs that regulate parental genes, or impacting nearby gene regulation through sequence insertion[3][5]. However, no such regulatory function is reported for EIF3LP3 itself in current literature or databases[1][2][4]. Key context: - EIF3LP3 is not a canonical drug target, receptor, or enzyme[1][2][4]. - Absence of functional or disease associations for this specific pseudogene. - The entry may be considered “incorrect” from the perspective of druggability or therapeutic targeting; it is not an established target[1][2][4]. Summary for structured data: - EIF3LP3 is a non-coding pseudogene, not a protein (nor therapeutic target); it does not belong to major drug target families and has no known direct role in disease or therapy[1][2][4][3][5].

Other names

EIF3LP3