Target intelligence / Profile preview

Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1)

Target: EIF4G1
Molecular classification: Scaffold protein, Translation initiation factor

Overview

EIF4G1 is a core component of the eIF4F protein complex, crucial for the initiation of eukaryotic translation. It acts as a scaffold protein, interacting with eIF4E, eIF4A, PABP, and eIF3 to facilitate mRNA recruitment to the ribosome. It's involved in immune signaling, glucose homeostasis, and neurological functions, and is implicated in Parkinson's Disease.

Other names: eIF4GEIF4FPARK18

Biological functions

Translation initiationmRNA cap recognitionRibosome recruitmentRegulation of protein synthesisImmune response

Disease associations

Parkinson DiseaseNeurological disorders

Beyond the preview

Go deeper on Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1).

Explore the full profile