Eukaryotic translation initiation factor 4A1 pseudogene 11 (EIF4A1P11)

Eukaryotic translation initiation factor 4A1 pseudogene 11 (EIF4A1P11) is a segment of human DNA that closely resembles the functional *eukaryotic translation initiation factor 4A1* (EIF4A1) gene, but it does not code for an active protein product[5][6]. Pseudogenes such as EIF4A1P11 result from duplication or retrotransposition events followed by loss of function, often due to mutations (such as premature stop codons or frameshifts)[6]. While the parent gene EIF4A1 encodes an important RNA helicase involved in translation initiation, pseudogenes like EIF4A1P11 do not contribute to protein synthesis, are not classified as enzymes, receptors, or other druggable target classes, and are not currently associated with any known drug interactions, mechanism of action, biomarker roles, or disease functions in the literature[2][5][6]. Misidentification of a pseudogene as a target can confound genetic or pharmacological research[6].\n\nIf your interest is in the functional protein, see **Eukaryotic translation initiation factor 4A1 (EIF4A1)**, which is a validated target and active translation factor[3][7]. But **EIF4A1P11** specifically refers to a nonfunctional genomic copy—**not a therapeutic target**.

Other names

EIF4A1P11

None