Eukaryotic translation initiation factor 4A1 pseudogene 2 (EIF4A1P2)

Eukaryotic translation initiation factor 4A1 pseudogene 2 (EIF4A1P2) is a non-coding pseudogene related to EIF4A1, which itself is a DEAD-box RNA helicase vital to eukaryotic mRNA translation initiation[2][3][4]. Pseudogenes such as EIF4A1P2 arise when duplicated or mutated versions of functional genes lose protein-coding ability. EIF4A1P2 is annotated in human genome databases but does not produce a functional protein, nor is it involved in translation, cellular signaling, disease biology, or targeted by any drugs. By contrast, EIF4A1 (eukaryotic translation initiation factor 4A1) is a well-characterized ATP-dependent RNA helicase, part of the eIF4F complex that unwinds mRNA secondary structures to facilitate ribosome recruitment and cap-dependent translation[2][3][4]. EIF4A1 is involved in cell proliferation, immune cell development, and acts as an oncogene in some cancers[1][4], but no such biological or therapeutic relevance applies to EIF4A1P2. EIF4A1P2 is an example of a gene name that may appear in bioinformatic searches but should not be listed as a drug target or functional receptor/enzyme/transporter. If querying for potential drug targets, focus on the parent gene EIF4A1 and not this pseudogene. If you intended to refer to EIF4A1 rather than its pseudogene, there is an error or misannotation in your query. EIF4A1P2 itself does not have known biological function, disease relevance, mechanism of action, or drug interactions.

Other names

EIF4A1P2