Eukaryotic translation initiation factor 4A1 pseudogene 9 (EIF4A1P9)

Eukaryotic translation initiation factor 4A1 pseudogene 9 (EIF4A1P9) is a non-coding pseudogene that shares sequence similarity with the protein-coding EIF4A1 gene[4][8]. Unlike the functional EIF4A1 protein, which is a member of the DEAD-box RNA helicase family involved in mRNA translation and is implicated in cancer progression, EIF4A1P9 does not produce a functional protein. Pseudogenes like EIF4A1P9 typically arise from gene duplication or retrotransposition events and can retain sequence homology to their parent genes, but most do not have independent biological or clinical significance[4][8][11]. Summary of incorrectness: This entry refers to a pseudogene and not an active gene product or therapeutic target. Pseudogenes are generally not drug targets as they do not encode proteins or function in the way true targets (such as receptors, enzymes, ion channels) do. There is no evidence from current authoritative gene/protein databases or the scientific literature that EIF4A1P9 has a functional biological role or is involved in disease, interacts with drugs, or acts as a biomarker[4][8][11]. Note: If you are seeking information on the functional protein target Eukaryotic translation initiation factor 4A1 (EIF4A1) (not pseudogene 9), that is a distinct entry and is a bona fide translation initiation factor and oncology target[7][9][10]. However, EIF4A1P9 is not.

Other names

EIF4A1P9