Eukaryotic translation initiation factor 4E binding protein 1 pseudogene 1 (EIF4EBP1P1)

Eukaryotic translation initiation factor 4E binding protein 1 pseudogene 1 (EIF4EBP1P1) is a human gene classified as a pseudogene of EIF4EBP1, the gene that encodes the protein 4E-BP1, an mRNA translation regulator. Pseudogenes like EIF4EBP1P1 lack the ability to encode a functional protein and are not known to have a direct therapeutic or functional biological role. Often, they are products of gene duplication or retrotransposition events; their functional significance, if any, is typically non-coding and regulatory, but for this specific gene, no evidence supports a role as a therapeutic target, nor does it have known disease associations or interactions with drugs[1][3][5][7][8]. Key interpretation and disambiguation: - This entry is a **pseudogene**, not a protein-coding gene or druggable target. - If the intended target was the protein-coding gene related to translation initiation (EIF4EBP1, i.e., 4E-BP1), which is a well-studied mTOR substrate and therapeutic interest in oncology, the correct entry would be Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1), not the pseudogene[2][4][6]. - Therefore, there is an issue with the target name: pseudogenes like EIF4EBP1P1 are not generally considered direct drug targets and do not meet typical "therapeutic target" criteria.

Other names

EIF4EBP1P4E-BP1 pseudogeneENSG00000258870[1][3][8]