Target intelligence / Profile preview

Eukaryotic translation termination factor 1 pseudogene 1 (ETF1P1)

Target
ETF1P1
Molecular classification
Other (pseudogene)
01

Overview

Eukaryotic translation termination factor 1 pseudogene 1 (ETF1P1) is a human pseudogene related to eukaryotic translation termination factor 1 (ETF1), which is an essential class-1 polypeptide chain release factor responsible for translation termination at stop codons. ETF1P1 itself does not encode for a functional protein. Like many pseudogenes, ETF1P1 is considered a nonfunctional relic of a protein-coding gene. Although some pseudogenes have emerging regulatory roles in gene expression (e.g., through acting as microRNA sponges or by generating regulatory noncoding RNAs), there is no direct evidence that ETF1P1 has any such functional impact. Its aliases include HCGVII and SUP45L2. ETF1P1 should not be confused with ETF1 (eukaryotic translation termination factor 1), which is a functional gene and an essential component of translation termination machinery.

Other names
HCGVIISUP45L2
02

Biological functions

Other (no direct biological function; as a pseudogene, may have potential RNA-mediated regulatory roles, but does not encode a functional protein)
03

Disease associations

Other (no direct, well-established disease association; some pseudogenes can regulate coding genes or participate in competing endogenous RNA networks, but ETF1P1 itself does not have a documented functional or pathological role as of current databases)

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