Target intelligence / Profile preview

Eva-1 homolog B (EVA1B)

Target
EVA1B
Molecular classification
Other (single-pass membrane protein, predicted), Paralog of Eva-1 homolog A (EVA1A)
01

Overview

Eva-1 homolog B (EVA1B) is a human protein encoded by the EVA1B gene, which is also known as FAM176B and C1orf78. It is a predicted single-pass membrane protein and the paralog of EVA1A, with its gene located on chromosome 1 (ENS00G000142694)[2][4][5][8]. EVA1B is predicted to be localized in membranes, but currently, there is little definitive information about its molecular function, biological roles, or disease relevance in humans. No evidence is available for its involvement as a therapeutic target, nor are there drugs, biomarkers, or safety concerns associated with it to date[2][4][8]. Note: Most available information refers to its structural features and gene family relationships rather than established functions or disease links, distinguishing it from EVA1A, which has well-characterized roles in autophagy and apoptosis[1].

Other names
C1orf78FAM176BFLJ10647Protein FAM176Bfamily with sequence similarity 176, member B
02

Biological functions

Unknown (no annotated function, predicted membrane localization)
03

Disease associations

Other (no known disease association, not reported as implicated in specific pathologies)

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