Excitatory neurotransmission in central nervous system

"Excitatory neurotransmission in the central nervous system" is not a specific molecule or receptor but rather describes a physiological process involving multiple molecules and receptors. This process refers to the transmission of signals between neurons that increase the likelihood of generating an action potential in the postsynaptic neuron, primarily mediated by excitatory neurotransmitters such as glutamate[1][3][4][5]. Glutamate acts on various ionotropic and metabotropic receptors to facilitate depolarization and neural signaling[4][5]. Dysregulation of excitatory neurotransmission is implicated in several neurological diseases, including neurodegenerative disorders and epilepsy[4]. However, this term does not refer to a single therapeutic target or molecular entity; instead, it encompasses a broad class of synaptic mechanisms and associated proteins. For structured data purposes, more specific targets within this pathway—such as "Glutamate receptor," "SLC1A3 (glutamate transporter)," or individual ion channels—should be used instead[2][4].\n\n**Note:** The entry is too broad for use as a canonical drug target; it should be replaced with specific molecular entities involved in excitatory neurotransmission.