Target intelligence / Profile preview

Exocyst complex component 1-like (EXOC1L)

Target
EXOC1L
Molecular classification
Other (pseudogene/protein coding, not classically categorized as receptor, enzyme, transporter, or transcription factor)
01

Overview

Exocyst complex component 1-like (EXOC1L) is a gene/protein in humans that encodes a protein similar to exocyst complex component 1, which is a key part of the exocyst complex required for targeting exocytic vesicles to specific sites on the plasma membrane[3][7]. While the canonical EXOC1 is an established member of the exocyst complex involved in vesicle trafficking and actin cytoskeletal remodeling[1][2], EXOC1L has much less functional annotation and is sometimes classified as a pseudogene or protein-coding gene with largely unknown biological significance[3][7]. No established therapeutic target, molecular function, or involvement in classical disease mechanisms is described for EXOC1L, and it does not appear in drug-targeting or biomarker registries[3][7]. The gene is sometimes referred to as a pseudogene, indicating possible non-coding or non-functional status in the current genomic annotation[3]. EXOC1L is often listed as a pseudogene or a protein-coding gene with unclear function and does not currently meet the definition of a therapeutic target such as a receptor, enzyme, transporter, or transcription factor[3][7]. There is risk of confusion with EXOC1, which is a well-characterized member of the exocyst complex involved in vesicle trafficking[1][2]. For EXOC1L, there is little to no published evidence for biological function, disease mechanisms, drug interactions, or use as a biomarker. The designation as a target is likely incorrect under current scientific knowledge.

Other names
EXOC1Lexocyst -like pseudogeneexocyst complex component 1 pseudogeneexocyst complex component 1 like
02

Disease associations

Fatal Familial Insomnia (reported as an associated condition in databases, but not as a causal or mechanistic role)

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