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F-box and WD repeat domain containing 4 pseudogene 1 (FBXW4P1)
- Target
- FBXW4P1
- Molecular classification
- Other (specifically, pseudogene of F-box/WD-40 family)
01
Overview
F-box and WD repeat domain containing 4 pseudogene 1 (FBXW4P1) is a human gene classified as a pseudogene; it does not encode a functional protein. The parent gene family, F-box/WD-40, is involved in protein degradation through ubiquitin-mediated pathways, relevant to developmental processes including limb formation. FBXW4P1 is distinct from the protein-coding FBXW4 gene, which has been associated through duplications and rearrangements with split hand/foot malformation (ectrodactyly), but this pseudogene itself is not a direct disease locus nor an active therapeutic target. Some aliases overlap with protein-coding forms and related pseudogenes, which may lead to confusion in nomenclature. If you require information about the protein-coding FBXW4 gene (not the pseudogene), it may have molecular functions and disease relevance, but FBXW4P1 itself has no established therapeutic, biomarker, or drug interaction data.
- Other names
- FBXW4P1FBW3FBXW3SHFM3P1F-box and WD-40 domain protein 3split hand/foot malformation (ectrodactyly) type 3 pseudogene 1F-box and WD repeat domain containing 4 pseudogene 1
02
Biological functions
Other (no known biological function; pseudogenes are typically non-functional, though some may have regulatory roles in rare cases)
03
Disease associations
Other (pseudogene itself not directly causal; however, the FBXW4 locus is implicated in split hand/foot malformation, but FBXW4P1 is not protein-coding and not associated with disease causation)
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