F-box only protein 36 (FBXO36)

F-box only protein 36 (FBXO36) is a member of the F-box protein family, which is defined by an approximately 40-amino acid F-box motif[1][6][9]. FBXO36 serves as the substrate-recognition component of the SKP1-CUL1-F-box (SCF) E3 ubiquitin ligase complex, where it helps recruit specific protein substrates for ubiquitination and subsequent proteasomal degradation[1][2][3]. The F-box family participates broadly in protein turnover by targeting select proteins for controlled destruction; however, the precise biological substrates and functions of FBXO36 in vivo remain undetermined[4]. There is no current evidence to suggest FBXO36 is a direct therapeutic target or is implicated in specific diseases, nor are there drugs or biomarkers known to be associated with it[4][1]. **Key Notes:** - FBXO36 is not a receptor, enzyme, transporter, or other common drug target class. - It has not been linked directly to any disease or therapeutic application in the literature. - Function is inferred from family membership rather than direct experimental studies. If further information on disease association or therapeutic targeting becomes available, these fields would be updated accordingly.

Other names

F-box only protein 36FBX36Fbx36FLJ37592FBXO36