Target intelligence / Profile preview

F11 antisense RNA 1 (F11-AS1)

Target: F11-AS1
Molecular classification: Long non-coding RNA (lncRNA), Antisense RNA

Overview

F11 antisense RNA 1 (F11-AS1) is a human long non-coding RNA gene located antisense to the F11 gene (which encodes coagulation factor XI). F11-AS1 belongs to the lncRNA gene class and functions as an antisense RNA, possibly modulating gene expression via epigenetic and transcriptional mechanisms. It has been implicated through genomic and expression studies in various cancers, including as a potential biomarker for disease status and prognosis (especially in liver cancer and glioma susceptibility). There is no current evidence that it interacts directly with drugs or serves as a validated receptor, enzyme, or transporter therapeutic target[6][1][3].

Other names: F11-AS1

Biological functions

Regulation of gene expression (by antisense transcription)Potential involvement in epigenetic regulation

Disease associations

Cancer (notably in liver cancer/hepatocellular carcinoma and glioma susceptibility)Co-mentioned with Factor XI deficiency (although this refers to the neighboring F11 gene and not necessarily to direct pathophysiology of F11-AS1)

Biomarkers

Potential biomarker for epigenetic changes in liver cancer and other malignancies

Beyond the preview

Go deeper on F11 antisense RNA 1 (F11-AS1).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Explore the programs pursuing this target and their development progress.

Drug candidates
Developers
Development stage

Clinical trials

Follow the clinical studies evaluating therapies directed at this target.

Trial design
Status
Readouts

Competitive landscape

Compare approaches across drug candidates, modalities, and indications.

Programs
Modalities
Indications

Literature & evidence

Investigate the research and source evidence behind target biology and development.

Publications
Sources
Analysis

Patents

Explore patent activity around therapies and technologies addressing this target.

Patents
Assignees
Technologies

Research & analysis

Connect target biology, drug development, and emerging evidence in your research.

Biology
Development news
Analysis

Bring the full picture into focus.

See how Gosset can support your research on F11 antisense RNA 1 (F11-AS1).

Explore the full profile