Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Factor Xa (FXa)
- Target
- FXa
- Molecular classification
- Serine endopeptidase, Serine protease, Enzyme
01
Overview
Factor Xa is the activated form of coagulation factor X, a serine endopeptidase that plays a central role in the blood coagulation cascade. It catalyzes the conversion of prothrombin to thrombin, a key step in clot formation. Inhibition of factor Xa is an effective strategy for anticoagulant therapy.
- Other names
- Activated Coagulation Factor XThrombokinase
02
Mechanism of action
Direct inhibition of Factor Xa, preventing the conversion of prothrombin to thrombin and subsequent clot formation.
03
Biological functions
Blood coagulationProthrombin activationThrombin generationFibrin formationMitogenesisGene expression regulation
04
Disease associations
ThrombosisVenous thromboembolismStrokeAtrial fibrillationBleeding disorders
05
Safety considerations
Bleeding riskReversal agents needed for life-threatening bleeds
06
Interacting drugs
Rivaroxaban
2 more in the full profile.
Beyond the preview
Go deeper on Factor Xa (FXa).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Factor Xa (FXa).