FAM135A antisense RNA 1 (FAM135A-AS1)

FAM135A antisense RNA 1 (FAM135A-AS1) is a long non-coding RNA (lncRNA) transcribed antisense to the FAM135A gene. Antisense lncRNAs such as FAM135A-AS1 function primarily through regulatory mechanisms, including modulation of the expression of their sense (protein-coding) counterparts, alteration of chromatin structure, and interference with transcription. These molecules may regulate gene expression at both the transcriptional and post-transcriptional levels, often through cis-acting effects near their sites of synthesis. As of now, FAM135A-AS1 is not characterized as a classical therapeutic target (such as a receptor, enzyme, transporter, etc.), and there is limited evidence directly connecting it to specific disease mechanisms or therapeutic interventions. Most available information focuses on the general regulatory roles of antisense lncRNAs in gene expression and possible broad involvement in cancer and cell differentiation[1][3][5][6][7].

Other names

FAM135A-AS1

Regulation of target mRNA stability or transcription through antisense pairing; Chromatin modification and transcriptional interference