Target intelligence / Profile preview

Family with sequence similarity 110 member D (FAM110D)

Target
FAM110D
Molecular classification
Other (uncharacterized protein)
01

Overview

Family with sequence similarity 110 member D (FAM110D) is a protein-coding gene that encodes a largely uncharacterized protein. FAM110D exhibits cytoplasmic and/or membranous expression in a wide range of human tissues[6]. Recent expression studies highlight notably high protein expression in endothelial cells and possible expression in granulosa cells[2]. Genetic studies have implicated FAM110D as a candidate gene for blood pressure regulation and hypertension risk, although its precise biological mechanism and role as a therapeutic target have not been established[4]. There are currently no known drugs interacting with FAM110D, and its specific molecular function remains undefined in the published literature[1][4][2].

Other names
GRRP1FLJ14050glycine/arginine-rich protein 1protein FAM110D
02

Biological functions

Unknownpossible involvement in blood pressure regulationpossible protein interactions in endothelial or granulosa cells
03

Disease associations

Hypertension (candidate gene in genetic association study)

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