Family with sequence similarity 118 member A (FAM118A)

Family with sequence similarity 118 member A (FAM118A) is a membrane-associated protein whose precise molecular function is not fully characterized but is known to enable identical protein binding and is predicted to be involved in nucleic acid binding[4][1]. It has been identified in the transcriptome of human osteoblasts, where it may influence traits like bone mineral density through a regulatory function, and it is differentially expressed in certain cancers—such as pancreatic adenocarcinoma and glioblastoma stem cells—where it may serve as a prognostic or diagnostic marker[1][6]. FAM118A also appears among molecular signatures distinguishing inflammatory responses in viral infections, supporting its potential utility as a biomarker, although no drugs or therapeutic mechanisms currently target this molecule[1][4]. Its biological roles and mechanisms in disease remain incompletely understood, and it has not been established as a validated therapeutic target.

Other names

C22orf8FLJ20635bK268H5.C22.4F118AFAM118Aprotein FAM118A