Family with sequence similarity 120A2, pseudogene (FAM120A2P)

Family with sequence similarity 120A2, pseudogene (abbreviated FAM120A2P), also known as C9orf129, bA165J3.3, and FAM120A2P pseudogene, is a human pseudogene with limited or no known protein-coding function.\n\nFAM120A2P encodes a pseudogene, meaning it is a genomic DNA sequence similar to a functional gene but generally considered non-functional due to accumulated mutations which prevent normal protein-coding[2][3][4]. Pseudogenes like FAM120A2P may arise from duplication or retrotransposition events. While most pseudogenes do not produce functional proteins, recent studies suggest some encode short peptides, can be transcribed into RNA, and may play regulatory roles, typically at the RNA level, such as acting as competing endogenous RNAs or regulating parental gene expression through microRNA binding[1][4][5].\n\nFAM120A2P is not established as a therapeutic target since there is no evidence of protein-coding or well-defined biological function, nor is it known to be involved in any specific disease process or interact with drugs[2][3][4]. It is best classified within \"Other\" molecular families as a non-coding or pseudogene, not in classical categories like receptors, enzymes, or transporters.\n\nWhile pseudogenes in some cases serve as sources for regulatory non-coding RNAs and may even encode short regulatory peptides, these properties are not confirmed for FAM120A2P itself. There are no associated drugs, biomarkers, or known safety concerns involving this pseudogene.

Other names

FAM120A2PC9orf129bA165J3.3FAM120A2P pseudogeneGC09M094273GC09M095449GC09M096687GC09M100608GC09M102075GC09M103395GC09M104761GC09M106159GC09M108104GC09M109901GC09M111840GC09M118602GC09M120652