Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Family with sequence similarity 13 member C (FAM13C)
- Target
- FAM13C
- Molecular classification
- Other (not a receptor, ion channel, enzyme, transporter, or transcription factor; belongs to the FAM protein family)
01
Overview
Family with sequence similarity 13 member C (FAM13C) is a protein-coding member of the FAM gene family, characterized by nuclear and/or cytoplasmic localization in most tissues, occasionally showing membranous expression. The biological function of FAM13C remains incompletely understood, but domain analyses and recent bioinformatics investigations suggest a role in intracellular signaling and cancer progression, especially in endometrial and prostate malignancies. FAM13C is considered a promising prognostic biomarker, with expression levels correlating to clinical outcomes in endometrial cancer. While the mechanistic basis of its activity is unclear, it is associated with cellular proliferation and may contribute to tumorigenesis. Currently, FAM13C is not the direct target of any approved therapies but holds potential as a future diagnostic and therapeutic target.
- Other names
- FAM13CFAM13C1Protein FAM13CFamily with sequence similarity 13, member CFamily with sequence similarity 13CFAM13CphFAM13CUniProt: Q8NE31A0A087X0M7A0A087X1H9
02
Mechanism of action
Not defined; therapeutic analyses are at the biomarker/prognostic level, no mechanism-based drug interactions established for FAM13C
03
Biological functions
Potential signal transductionCell proliferationImplicated in intracellular signaling pathways relevant to cancerPossibly involved in regulation of cell survival and cell cycle progression via domain structure, but not fully characterized
04
Disease associations
Cancer (prostate cancer, endometrial cancer, mixed adenocarcinoma, breast and gynecological cancers)Prognostic biomarker for endometrial cancer (UCEC)
05
Safety considerations
None reported, as FAM13C is not currently a direct drug target; concerns would be speculative due to incomplete functional characterization
06
Biomarkers
Prognostic biomarker in endometrial cancer (low expression associated with poor disease-specific survival)Potential diagnostic marker for tissue distinction in cancer
Beyond the preview
Go deeper on Family with sequence similarity 13 member C (FAM13C).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Family with sequence similarity 13 member C (FAM13C).