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Family with sequence similarity 131 member C (FAM131C) is a human protein-coding gene coding for a protein that undergoes N-myristoylation, a lipid modification that typically determines subcellular localization and protein interactions[1][5]. FAM131C has not been directly linked to human diseases nor is it established as a therapeutic target or drug-interacting protein. Animal model data (porcine cells) suggest FAM131C can suppress innate immune gene expression and thereby increase susceptibility to certain viral infections by negatively regulating host antiviral responses[2]. FAM131C is encoded on chromosome 1, is conserved across species, presents with multiple transcript variants, and does not belong to any major molecular target class such as receptor, enzyme, or transporter[5][4].
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