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Family with sequence similarity 136 member E, pseudogene (FAM136EP) is formally annotated as a pseudogene. Pseudogenes are DNA sequences that resemble functional genes but generally lack the ability to encode a functional protein, often due to disabling mutations, truncations, or the absence of regulatory elements required for expression[1][5]. Although pseudogenes may be transcribed into noncoding RNAs, and some have been shown to modulate the function of related coding genes through mechanisms such as serving as decoys for microRNAs or producing small interfering RNAs, there is no evidence that FAM136EP encodes a protein or serves as a conventional molecular target in therapeutic contexts[1][3]. As such, FAM136EP is not considered a therapeutic target and would not normally be included in drug discovery or molecular targeting pipelines[5].
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