Family with sequence similarity 138 member D (FAM138D)

Family with sequence similarity 138 member D (FAM138D) is a gene encoding a putative 85-amino acid polypeptide, also referred to as F379 retina-specific protein[2][3][6]. This gene was initially identified as being specifically expressed in the human retina, mapped to subtelomeric regions of multiple chromosomes, and appears to be duplicated in a polymorphic manner[2]. The protein does not show significant homology to known functional protein domains or established molecular families outside of sequence elements (Alu and MIR repeats) and currently has no confirmed known biological function, disease association, or therapeutic targeting role[2][3][6][8]. Its naming and expression profile support a role as a retina-specific gene, but current literature and databases offer no evidence of involvement in any major molecular pathways, no identified small molecule or therapeutic interactions, and it is not classified as an established target for drug development.

Other names

F379F379 retina-specific proteinFAM138DFAM138F (possible related protein)chromosome 1 F379 retina-specific protein