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FAM153B refers to "Family with sequence similarity 153 member B," annotated in the human genome as a **pseudogene** rather than a protein-coding gene. While the nomenclature suggests the presence of a functional protein family, in humans FAM153B does not encode a protein and has no established role as a therapeutic target, receptor, enzyme, or transporter. Some genetic databases mention distant associations with diseases (such as familial hemiplegic migraine), but there is no mechanistic or pharmacological validation for target action or drug interaction. FAM153B therefore does not belong to any well-established molecular or functional family relevant for drug discovery and is generally excluded from target nomination lists[9][1][11].
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