Family with sequence similarity 166 member A, pseudogene (FAM166A, pseudogene)

FAM166A, pseudogene (Ensembl: ENSG00000277099) is a genomic DNA segment that shares high sequence similarity with the protein-coding gene Family with sequence similarity 166 member A (FAM166A) but is classified as a pseudogene because it has mutations or structural differences preventing it from being translated into a functional protein[5][6]. Pseudogenes often result from duplication or retrotransposition events and may lack regulatory sequences, have truncated exons, or harbor mutations such as frameshifts or premature stop codons, rendering them nonfunctional at the protein level[5][1]. Some pseudogenes participate in transcription and can produce non-coding RNAs that may play roles in gene regulation (for example, by acting as competing endogenous RNAs, miRNA sponges, or sources of small interfering RNAs)[1][3][7]. However, there is no evidence that FAM166A, pseudogene acts as a therapeutic target, produces protein, or has direct clinical relevance.

Other names

FAM166A pseudogene