Family with sequence similarity 180 member A (FAM180A)

Family with sequence similarity 180 member A (FAM180A) is a protein-coding gene found in humans and other mammals, initially described based on its sequence homology rather than a defined biological function. Current evidence suggests the encoded protein is likely secreted and localized to the extracellular region[1][5]. FAM180A has no well-characterized molecular function, pathway, or disease mechanism, and neither pharmacological modulators nor clinical relevance as a drug target have been described. There is no evidence that it acts as a canonical therapeutic target such as a receptor, enzyme, transporter, or transcription factor. Research indicates some sequence conservation and there are limited associations with bone-related sarcomas, but functional studies are lacking, and its role—if any—in pathophysiology or therapy remains undefined[5][3][1].

Other names

Protein FAM180AUNQ1940/PRO4423HWKM1940UNQ1940protein FAM180A