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Target intelligence / Profile preview
Family with sequence similarity 181 member A (FAM181A)
- Target
- FAM181A
- Molecular classification
- Protein-coding gene, Nuclear protein (localizes to the nucleus), Putative transcriptional regulator or transcription factor interactor
01
Overview
Family with sequence similarity 181 member A (FAM181A) encodes a nuclear protein that is conserved in mammals, insects, and fish. It contains a putative Ω-loop similar to regions found in transcriptional regulators like YAP, suggesting it may interact with the TEAD family of transcription factors. Current research indicates FAM181A is involved in nervous system development and may function as a transcriptional co-regulator, but its specific biological role is not well established. There is no evidence supporting its consideration as a therapeutic target, disease biomarker, or drug target, nor are there known safety concerns related to this molecule
- Other names
- FAM181AF181A protein
02
Biological functions
Nervous system developmentPutative interaction with TEAD transcription factors (may modulate transcriptional activity)
03
Disease associations
Other (Limited evidence for disease association; possible involvement in neurodevelopment via interaction networks)
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