Family with sequence similarity 184 member B (FAM184B)

Family with sequence similarity 184 member B (FAM184B) is a human protein encoded by the FAM184B gene (also known as KIAA1276) located on chromosome 4[3][10][12]. It belongs to the FAM184 protein family, with its closest paralog being FAM184A[3]. FAM184B is a protein of unknown function and currently lacks definitive classification as a receptor, enzyme, transporter, or other well-established drug target class[3][7][12]. It has been associated through genetic studies with certain syndromes, such as Weyers acrofacial dysostosis and Usher syndrome, but its precise biological role, molecular function, or involvement in canonical cell signaling and disease pathways remains uncharacterized[3]. Tissue expression analysis shows cytoplasmic presence in heart and skeletal muscle, but there is limited evidence linking it to therapeutic targeting or direct drug interaction[5].

Other names

Protein FAM184BKIAA1276