Family with sequence similarity 185 member A (FAM185A)

Family with sequence similarity 185 member A (FAM185A) is a protein-coding gene found at chromosome 7q22.1, encoding a mitochondrial-localized protein with multiple DUF4098 domains whose biological function remains largely unknown[1][3][4]. It is moderately expressed in brain, cerebral cortex, retina, skin, bone marrow, adrenal gland, and muscle—especially in fetal tissues relative to adult[3]. Evidence suggests possible involvement in regulatory pathways related to immune function (e.g., neutrophil activation in thymoma) and exercise adaptation, but definitive molecular function and clinical relevance have not been validated[1][3][4][7]. There are no confirmed direct protein-protein interactions, and only mouse data suggests possible chemical interaction partners[3]. No diseases have been directly linked to mutations in FAM185A, and it is not a recognized therapeutic target or validated biomarker[4][7].

Other names

FAM185AProtein FAM185AMGC35361Fam185aF185A