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Target intelligence / Profile preview
Family with sequence similarity 186 member A (FAM186A)
- Target
- FAM186A
- Molecular classification
- Other
01
Overview
Family with sequence similarity 186 member A (FAM186A) is a protein-coding gene of yet unknown function in humans. Recent genomic and transcriptomic studies implicate FAM186A in cancer biology, with coding variants associated with increased colorectal cancer risk and expression changes seen during hepatocellular carcinoma progression, yet its precise molecular or cellular role is uncharacterized. It is not an established receptor, enzyme, or therapeutic target, nor is it presently classified in any major molecular target family, and no drugs or known ligands interact with it at this time[1][2][3][4][5].\n\nFAM186A is cataloged in major genetic databases (HGNC: 26980, NCBI Gene: 121006, Ensembl: ENSG00000185958, UniProt: A6NE01)[3][4]. Current evidence suggests research relevance in disease genomics, especially oncology, but not therapeutic biology.
- Other names
- FAM186AProtein FAM186ALOC121006F186A_HUMAN (UniProt)GC12M049009GC12M050721GC12M047754
02
Mechanism of action
None identified
03
Biological functions
Other
04
Disease associations
CancerOther
05
Safety considerations
None reported
06
Interacting drugs
None identified
07
Biomarkers
None established
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