Family with sequence similarity 186 member B (FAM186B)

Family with sequence similarity 186 member B (FAM186B) is a human protein encoded by the FAM186B gene, also known as C12orf25. The protein is predicted to be part of a protein-containing complex, but its specific molecular function, biological pathway involvement, or roles in cell physiology are currently unknown. Limited functional characterization is available; data indicate it is a protein-coding gene with several splice variants and is expressed in various tissues (including large intestine, kidney, ovary, and testis). There is some genetic association with juvenile nephronophthisis and nephronophthisis, but there is no evidence FAM186B is a clinically relevant therapeutic target, nor are any drugs or specific mechanisms of action known for this protein[1][3][6][10].

Other names

C12orf25DKFZP434J0113protein FAM186BFAM186B