Family with sequence similarity 200 member C (FAM200C)

Family with sequence similarity 200 member C (FAM200C) is a human protein encoded by the FAM200C gene, also known by aliases such as ZBED8, C5orf54, and Buster3. It is classified as a protein coding gene, with known localization to the nucleoplasm and suggested molecular features including a zinc finger BED domain, which typically mediates DNA binding or chromatin association[3][5]. The gene's function, biological pathways, involvement in disease, and role as a therapeutic target are currently uncharacterized in the literature and major databases[3][2]. There is no evidence it functions as an enzyme, receptor, transporter, or recognized therapeutic target. This protein should not be confused with FAM20C, a well-characterized secreted protein kinase implicated in multiple diseases, including cancer and abnormal mineralization[1]. As such, FAM200C (ZBED8) is not an established drug target, and some sources may incorrectly conflate it with FAM20C due to similar gene symbols or aliases.

Other names

Protein FAM200CBuster3C5orf54ZBED8protein ZBED8transposon-derived Buster3 transposase-like proteinzinc finger BED domain-containing protein 8zinc finger BED-type containing 8