Family with sequence similarity 219 member A (FAM219A)

Family with sequence similarity 219 member A (FAM219A) is a human protein encoded by the C9orf25 gene, located on chromosome 9 at 9p13.3. The protein is composed of 185 amino acids, with a molecular weight of 20.4 kDa and predicted cytosolic localization, lacking a signal sequence. It belongs to the FAM219 superfamily (Pfam PF15260), but remains a domain of unknown function, with no clear catalytic, receptor, or transport roles as of current knowledge. FAM219A is expressed in many tissues, with higher expression in the nervous, digestive, and male reproductive systems. Multiple transcript variants exist, with some encoding protein isoforms. FAM219A interacts with diverse proteins, some of which have disease associations, but it is not itself directly implicated in pathology. Experimental evidence for its biological process or molecular function is still lacking; therefore, it is currently categorized as a protein with unknown function and has no established therapeutic significance.

Other names

FAM219AC9orf25bA573M23.5FLJ39031protein FAM219Auncharacterized protein C9orf25family with sequence similarity 219 member A

None known. No mechanisms of drug action are described for this molecule.