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Family with sequence similarity 223 member B (non-protein coding) (FAM223B)

Target
FAM223B
Molecular classification
Long non-coding RNA (lncRNA), Long intergenic non-coding RNA (lincRNA), Other: Non-protein coding gene
01

Overview

Family with sequence similarity 223 member B (FAM223B) is classified as a long intergenic non-protein coding RNA (lincRNA), implicated in gene regulation at the transcriptional, post-transcriptional, or epigenetic level[3][4][8]. FAM223B is a non-protein coding gene also referred to as LINC00204B, encoding a lincRNA transcript rather than a protein. While lincRNAs can control gene expression programs and have roles in development, cell differentiation, and disease states, there is no direct evidence for a therapeutic target function or specific disease association for FAM223B. Current knowledge does not establish FAM223B as involved with drug mechanisms, biomarker selection, or clinical safety challenges[3][4][8]. Note: Some of the aliases and database entries may contain closely related gene symbols typical for non-coding RNA annotation, but no conflicts or major errors are detected in the form or spelling of this target. FAM223B is indexed as a non-protein coding gene, not as a receptor, enzyme, or other canonical drug target class[3][4][8].

Other names
Protein FAM223BFAM223BCXorf52BLINC00204BCXorf52NCRNA00204BFamily with sequence similarity 223 member B (non-protein coding)Long intergenic non-protein coding RNA 204BNon-protein coding RNA 204B
02

Biological functions

Likely regulation of gene expression (inferred from molecular class)[4][8]Other (as specific molecular function not established; lincRNAs generally act in transcriptional, epigenetic, or post-transcriptional regulation)[4][8]
03

Disease associations

Other (evidence for disease involvement not established for FAM223B specifically; generalized to non-coding RNAs in gene regulation and disease)[4][8]

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