Family with sequence similarity 230 member D (FAM230D)

FAM230D is a member of the FAM230 gene family, defined by sequence similarity in particular chromosomal regions (notably chromosome 22 LCRs/LCR22s). It is annotated as a long intergenic non-coding RNA (lincRNA) gene, meaning it is transcribed but does not encode a protein product^5. These lincRNA genes are part of a repeated genomic structure involving clincRNA sequences, spacers, and pseudogenes, which are implicated in gene family expansion and chromosomal segmental duplications. The specific biological function of FAM230D remains uncharacterized; related FAM230 lincRNAs exhibit tissue-specific expression (e.g., testes and fetal heart) and may be involved in development, but direct evidence for regulatory roles or disease association is lacking^5. FAM230D should not be confused with similarly named protein-coding genes (e.g., FAM83D) that are implicated as cancer biomarkers or therapeutic targets[1][3]. No drugs, mechanisms of action, or clinical safety data have been reported for FAM230D due to its non-coding RNA nature^5.

Other names

AC008079.1