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Family with sequence similarity 238 member C (non-protein coding) (FAM238C)
- Target
- FAM238C
- Molecular classification
- Long intergenic non-coding RNA (lincRNA), Long non-coding RNA (lncRNA), Non-coding RNA
01
Overview
Family with sequence similarity 238 member C (FAM238C) is a long intergenic non-coding RNA (lincRNA) gene that does not code for a protein but may perform regulatory functions at the RNA level. The FAM238C gene is found on human chromosome 10 and is also known by aliases related to genomic mapping and possibly past annotation as a lincRNA. Like other lincRNAs, FAM238C may regulate chromatin structure, transcription, or mRNA stability, although no specific biological function or mechanism has been demonstrated for this gene. FAM238C and related gene family members often carry highly repetitive AT-rich DNA translocation motifs and are particularly expressed in the testes. There are no known direct disease associations, drug interactions, or recognized uses as a biomarker or therapeutic target for FAM238C.
- Other names
- C10orf51LINC00202LINC00202-1NCRNA00202bB27G4.1family with sequence similarity 236 member C (non-protein coding)family with sequence similarity 238 member C (non-protein coding)long intergenic non-protein coding RNA 202long intergenic non-protein coding RNA 202-1
02
Mechanism of action
None reported
03
Biological functions
Chromatin remodeling and genome architecture (general lincRNA role)Regulation of transcription (general lincRNA role)RNA stabilization (general lincRNA role)Possible tissue-specific gene regulation (noted to be specifically expressed in testes)Other (function of FAM238C itself is unknown)
04
Disease associations
Other (no direct disease association for FAM238C itself, but related genes may be implicated in chromosomal instability; the critical region 22q11.2 harboring related genes is linked to genetic disorders)
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