Family with sequence similarity 24 member B (FAM24B)

Family with sequence similarity 24 member B (FAM24B) is a human protein encoded by a protein-coding gene located on chromosome 10. It is primarily found in the extracellular region and is predicted to act as a local modulator of key ion transporters, such as V-ATPase and CFTR, often enhancing or inhibiting their activities[3][9][13]. Its protein domain and biological pathway annotations remain limited, and its molecular functions are not fully identified[10]. FAM24B is considered a potential prognostic biomarker in certain cancers due to its methylation and gene expression patterns, but is not currently recognized as a typical drug target, nor does it have well-established therapeutic or receptor-like roles[5][2]. Detection of FAM24B or its methylation status may assist in prognosis or cancer subtype classification, although clinical utility has yet to be systematically established.

Other names

Protein FAM24BMGC45962AC073585.2FAM24BFA24BHGNC:23475NCBI Gene:196792Ensembl: ENSG00000213185UniProtKB: Q8N5W8

None (no drugs are known to target FAM24B, and molecular mechanism remains to be defined)