Target intelligence / Profile preview

Family with sequence similarity 245 member A (FAM245A)

Target
FAM245A
Molecular classification
Long intergenic non-coding RNA (lincRNA), Non-coding RNA, Pseudogene (has been annotated as a cathepsin-L-like pseudogene in some databases)
01

Overview

Family with sequence similarity 245 member A (FAM245A), also known as LINC00864, is a long intergenic non-coding RNA (lincRNA) gene in humans[1][3]. lincRNAs are autonomously transcribed non-coding RNAs longer than 200 nucleotides that do not overlap protein-coding genes[4]. FAM245A does not encode a protein but may contribute to the regulation of chromatin state, genome architecture, and gene expression, often with tissue-specific effects typical of lincRNAs[4]. Some aliases (e.g., “cathepsin L-like 1 (pseudogene)”) arose from older annotations labeling it as a pseudogene, but there is no evidence it encodes a functional protein or acts as a traditional therapeutic target such as a receptor, enzyme, transporter, or transcription factor[1][3]. No direct disease association, drug interaction, biomarker, or major therapeutic relevance is established for FAM245A based on current sources.

Other names
LINC00864Long intergenic non-protein coding RNA 864CTSL1P1CTSLLCTSLL1Cathepsin L-like 1 (pseudogene)Cathepsin L1 pseudogene 1CTSLP1
02

Mechanism of action

Not applicable, as no direct drug interactions are documented

03

Biological functions

Chromatin remodeling and genome architecture (as typical for lincRNAs)RNA stabilizationRegulation of transcription (including enhancer-associated activity)Modulation of gene expression, often in a tissue-specific mannerFine-tuning the expression of neighboring genes
04

Disease associations

Other (No evidence in the search results for direct involvement in specific major disease categories)

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